Chronopharmaceutics: Science and Technology for Biological Rhythm Guided Therapy and Prevention of Diseases

ACKNOWLEDGMENTS.

CONTRIBUTORS.

ABBREVATION LIST.

INTRODUCTION: TIME, DIAGNOSTICS, AND THERAPEUTICS—BEYOND CIRCADIAN MARKER RHYTHM-GUIDED TREATMENT (Franz Halberg, Germaine Corne lissen, and Othild Schwartzkopff).

1 OVERVIEW OF CHRONOPHARMACEUTICS (Bi-Botti C. Youan).

2 CHRONOGENETICS (Franck Delaunay).

3 CHRONOPHARMACOKINETICS (Bernard Bruguerolle).

4 CHEMICAL OSCILLATOR SYSTEMS FOR CHRONOTHERAPY (Steven A. Giannos).

5 DIFFUCAPS TECHNOLOGY FOR CONTROLLED RELEASE DRUG DELIVERY (Gopi Venkatesh).

6 CHRONOTOPICt TECHNOLOGY (M. E. Sangalli, A. Maroni, L. Zema, M. Cerea, and A. Gazzaniga).

7 CHRONOTHERAPY USING EGALET TECHNOLOGY (Daniel Bar-Shalom, Clive G. Wilson, and Neena Washington).

8 CHRONSETt: AN OROS DELIVERY SYSTEM FOR CHRONOTHERAPY (Liang C. Dong, Crystal Pollock-Dove, and Patrick S.L. Wong).

9 CONTROLLED RELEASE MICROCHIPS (Karen Daniel, Hong Linh Ho Duc, Michael Cima, and Robert Langer).

10 IMPLICATIONS AND APPLICATIONS OF CIRCADIAN SUSCEPTIBILITY RHYTHMS: CHRONOMICS AND ANESTHESIA (Franz Halberg, Germaine Corne´ lissen, and Othild Schwartzkopff).

11 TREATMENT WITH OPEN EYES: MARKERS-GUIDED CHRONOTHERANOSTICS (Germaine Corne lissen, and Franz Halberg).

INDEX.