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Pharmaceutical Salts: Properties, Selection, and Use, 2nd Revised Edition

ISBN: 978-3-90639-051-2
Hardcover
388 pages
April 2011
List Price: US $235.00
Government Price: US $135.63
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Pharmaceutical Salts: Properties, Selection, and Use, 2nd Revised Edition (3906390519) cover image

Introduction (Camille G. Wermuth and P. Heinrich Stahl).

Chapter 1. The Physicochemical Background: Fundamentals of Ionic Equilibria (Michael B. Maurin, David J. W. Grant, and P. Heinrich Stahl).

Chapter 2. Solubility and Dissolution of Weak Acids, Bases, and Salts (Madhu Pudipeddi, Abu T. M. Serajuddin, David J. W. Grant, and P. Heinrich Stahl).

Chapter 3. Evaluation of Solid-State Properties of Salts (Danielle Giron and David J. W. Grant).

Chapter 4. Pharmaceutical Aspects of the API Salt Form (P. Heinrich Stahl and Finlay S. Skinner).

Chapter 5. Biological Effects of the API Salt Form (Friedlieb Pfannkuch, Harald Rettig, and P. Heinrich Stahl).

Chapter 6. Salt-Selection Strategies (Abu T. M. Serajuddin and Madhu Pudipeddi).

Chapter 7. A Procedure for Salt Selection and Optimization (Michael J. Bowker).

Chapter 8. High-Throughput Strategies and Techniques for Salt Screening (Nicole Wyttenbach, Bertrand Sutter, and Pirmin Hidber).

Chapter 9. Large-Scale Aspects of API Salt Manufacture (Piotr H. Karpiński).

Chapter 10. Patent Aspects of API Salt Formation (Hans-Günther Foraita).

Chapter 11. Regulatory Aspects of API Salts (Maria Arfwedson and Alan Chalmers, Jun-ichi Kondo and P. Heinrich Stahl, and Mansoor A. Khan and Vilayat A. Sayeed).

Chapter 12. Selected Procedures for the Preparation of Pharmaceutically Acceptable Salts (Camille G. Wermuth and P. Heinrich Stahl).

Chapter 13. Monographs on Acids and Bases (P. Heinrich Stahl and Camille G. Wermuth).

Appendix (P. Heinrich Stahl).

Subject-Index.

Substance-Index.

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