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Prodrugs and Targeted Delivery: Towards Better ADME Properties

Jarkko Rautio (Editor), Raimund Mannhold (Series Editor), Hugo Kubinyi (Series Editor), Gerd Folkers (Series Editor)
ISBN: 978-3-527-32603-7
Hardcover
520 pages
December 2010
List Price: US $205.00
Government Price: US $138.19
Enter Quantity:   Buy
Prodrugs and Targeted Delivery: Towards Better ADME Properties (3527326030) cover image
Other Available Formats: E-book

This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs.
Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.
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