Mass Spectrometry in Medicinal Chemistry: Applications in Drug Discovery

Mass Spectrometry in Bioanalysis -
Methods, Principles and Instrumentation
Drug Screening Using Gel Permeation Chromatography Spin Columns Coupled with ESI-MS
ALIS: An Affinity Selection-Mass Spectrometry System for the Discovery and Characterization of Protein-Ligand Interactions
Library Screening Using Ultrafiltration and Mass Spectrometry
Continuous-Flow Systems for Ligand Binding and Enzyme Inhibition Assays Based on Mass Spectrometry
Frontal Affinity Chromatography -
Mass Spectrometry for Ligand Discovery and Characterization
MS-Binding Assays - an Alternative to Radioligand Binding
Laser Desorption Assays -
MALDI-MS, DIOS-MS, and SAMDI-MS
Tethering: Fragment-Based Drug Discovery by Mass Spectrometry
Interrogation of Noncovalent Complexes by ESI-MS: A Powerful Platform for High Throughput Drug Discovery
Quantification of Protein-Ligand Interactions in Solution by H/D Exchange (PLIMSTEX)
Protein-Targeting Drug Discovery Guided by Hydrogen/Deuterium Exchange Mass Spectrometry (DXMS)
Mass Spectrometry in Early Pharmacokinetic Investigations