The Way of Synthesis: Evolution of Design and Methods for Natural Products

INTRODUCTION
The History of Synthesis
Milestones in Organic Sythesis
STRATEGY AND TACTICS
Principles and Issues Impacting Synthesis (Strategy)
Principles and Issues Impacting Design (Strategy)
Principles and Issues of Methods (Tactics)
COMPARATIVE DESIGN: CLASSICS IN TERPENE SYNTHESIS
Juvenile Hormones
Cedrenes
Zizaanes
Hydroazulenes
Vernolepin
Triquinanes
Compactin
Aphidicolin
Miscellaneous Diterpenes
Taxol
COMPARATIVE DESIGN: CLASSICS IN ALKALOID SYNTHESIS
Lycopodium Alkaloids
Daphniphyllum Alkaloids, Daphnilactone A
Pyrrolizidine Alkaloids
Amaryllidaceae Alkaloids
Morphine
Indole Alkaloids
MISCELLANEOUS SYNTHESES
Maytansine
Palytoxin
Brevetoxin B
Indinavir
OUTLOOK