Molecular Biology in Medicinal Chemistry

Theodor Dingermann (Editor), Dieter Steinhilber (Editor), Gerd Folkers (Editor), Raimund Mannhold (Series Editor), Hugo Kubinyi (Series Editor)

ISBN: 978-3-527-30431-8

Hardcover

435 pages

February 2004

List Price:	US $265.00
Government Price:	US $155.47
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Molecular Biology in Medicinal Chemistry (3527304312) cover image

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MOLECULAR TARGETS
Cellular Assays in Drug Discovery
Gene Knockout Models
Reporter Gene Assay Systems for the Investigation of GPCRs
From the Human Genome to New Drugs: The Potential of Orphan GPCRs
SYNTHESIS
Stereoselective Synthesis with the Help of Recombinant Enzymes
Nucleic Acid Drugs
ANALYSIS
Recent Trends in Enantioseparation of Chiral Drugs
Affinity Chromatography
NMR-based Drug Discovery
13C- and 15N-Isotopic Labeling of Proteins
Antibody Fragments as Crystallization Enhancers
KINETICS, METABOLISM AND TOXICOLOGY
Pharmacogenetics: The Effect of Inherited Genetic Variation on Drug Disposition and Drug Response
Pharmacogenomics of Bioavaliability and Elimination
Toxicogenomics: Integration of New Molecular Biological Tools in Toxicology