NMR Spectroscopy in Drug Development and Analysis

Introduction
Regulatory Remarks on Drug Analysis
Analysis of Drugs
pH-Dependent NMR Measurements
Complexation of Drugs with Small Molecules
Determination of the Isomeric Composition of Drugs
On-Line Coupling of Chromatographic Separation Techniques with NMR Spectroscopy
NMR of Body Fluids
Solid-State NMR in Drug Analysis
NMR Studies of Protein-Ligand Interactions for Drug Design
Complexation of Drugs with Large Molecules
Ligand-Cyclodextrin Complexes
NMR Imaging
Concluding Remarks