Skeletal Biology and Medicine, Volume 1192

The 2nd Conference on Skeletal Medicine and Biology: SpecialFeatures: Mone Zaidi.

Historical Reflections and the Future: IainMacIntyre.

Part I: Bone and Blood Vessels:.

1. Oxygen Sensing and Osteogenesis: Ying Wang, Chao Wan, ShawnR. Gilbert, and Thomas L. Clemens.

2. Perspective: The Osteoclast: An Angiogenic Cell?: Frank C.Cackowski and G. David Roodman.

3. Fetal Growth Plate: A Developmental Model of CellularAdaptation to Hypoxia: Sylvain Provot and Ernestina Schipani.

4. Vascular Bmp-Msx2-Wnt Signaling And Oxidative Stress InArterial Calcification: Jian-Su Shao, Ziyad Al Aly, Chung-Fang Lai,Su-Li Cheng, Jun Cai, Emily Huang, Abe Behrmann, and Dwight A.Towler.

5. Hypoxia-Mediated Mitochondrial Stress in RAW 264.7 CellsInduces Osteoclast-Like TRAP Positive Cells: Satish Srinivasan, andNarayan G. Avadhani.

6. Stem Cell Therapy in Bone Repair and Regeneration: NeehaZaidi and Alan J. Nixon.

7. Fluid Shear Stress Up-regulates Vascular Endothelial GrowthFactor Gene Expression in Osteoblasts: Mia M. Thi, Dumitru A.Iacobas, Sanda Iacobas, and David C. Spray.

Part II: Skeltal Immunity and Inflamation:.

8. B Lymphocytes and the Skeleton: Mark C. Horowitz.

9. Vitamin D in Defense of the Human Immune Response: John S.Adams, Philip T. Liu, Rene Chun, Robert L. Modlin, and MartinHewison.

10. MRI and Quantification of Draining Lymph Node Function inInflammatory Arthritis: Steven T. Prouvélx, Edmund Kwok, Zhigang You,Christopher A. Beck, David J. Shealy, Christopher T. Ritchlin,Brendan F. Boyce, Lianping Xing, and Edward M. Schwarz.

11. Perfusion Abnormalities in Subchondral Bone Associated withMarrow Edema, Osteoarthritis, and Avascular Necrosis: Roy K. Aaron,Jonathan P. Dyke, Deborah McK. Ciombor, Glenn A. Tung.

12. Nuclear Factor of Activated T cell Mediates ProinflamatoryGene Expression in Response to Mechanotransduction: Ayse B. CelilAydemir, Stephenie Lee, Dae Won Kim, Thomas R. Gardner, DanielPrince, Jae Mok Ahn, and Francis Young-In Lee.

13. Orthopaedic Implant Particle-Induced Tumor Necrosis Factor-Production in Macrophage/Monocyte Lineage Cells is Mediated byNuclear Factor of Activated T cells: Hiroshi Minematsu, Mike J.Shin, Ayse B. Celil Aydemir, Sung Wook Seo,Dae Won Kim, Theodore A.Blaine, Fernando Macián, Jay Yang, Francis Young-In Lee.

14. ERK Signaling Regulates M-CSF Expression Induced By TitaniumParticles In MC3T3.E1 Murine Calvarial Preosteoblastic Cells.

15. Sung W. Seo, Daniel Lee, Samuel K Cho, Abraham D. Kim,Hiroshi Minematsu, Ayse B. Cecil Aydemir, Jeffrey A. Geller,William Macaulay, Jay Yang, Francis Y. Lee.

16. Synovial Fluid Fibroblasts and Lymphocytes Support theOsteoclastogenesis in Human Psoriatic Arthritis: Giorgio Mori,Francesco P. Cantatore, Giacomina Brunetti, Angela Oranger,Graziana Colaianni, Laura Quarta, Addolorata Corrado, SilviaColucci, and Maria Grano.

17. Molecular and Histological Analysis of A New Rat Model ofExperimental Knee Osteoarthritis: C. Thomas G. Appleton, David D.McErlain, James L. Henry, David W. Holdsworth and Frank Beier.

18. Expression of MIG-6, WNT-7B and WNT-9A DuringOsteoarthritis: Cristina Velasquillo, DavidGarciadiego-Cázares, Maylin Almonte, Marcia Bustamante,Clemente Ibarra, Juan B. Kouri, Jesús Chimal-Monroy.

19. Calcitonin Affects Both Bone and Cartilage - A Possible DualAction Tratment for Osteoarthritis?: Morten A. Karsdal, Bodil C.Sondergaard, Michel Arnold, Claus Christiansen.

Part III: Clinical and Therapeutic Challenges in Bone andJoint Disease:.

20. Progress, Paradox and Potential: Parathyroid Hormone (PTH)Research Over Five Decades: John T. Potts, and Thomas J.Gardella.

21. Bisphosphonates: From Bench to Bedside: Graham Russell.

22. Future Developments in Therapy: Carlos M. Isales and Jay M.McDonald.

23. Selecting Patients at Risk of Osteoporotic Fracture: TheProposed WHO risk platform: Stuart L. Silverman.

24. Progression of Efficacy With Ibandronate – A ParadigmFor The Development of New Bisphosphonates: Mone Zaidi, SolomonEpstein, Steven T. Harris, Joseph D. Kohles,Charles H. Chesnut.

25. Rationale for Using Nitric Oxide Donor Therapay forPrevention of Bone Loss and Treatment of Osteoporosis in Humans:Sunil J. Wimalawansa.

26. Proteasome Inhibitors Stimulate both Bone Formation and HairGrowth by Similar Mechanisms: Gregory Mundy, Gloria Gutierrez, RossGarrett, Wolfgang Gallwitz, Gianni Rossini, Claus Christiansen, andAndria Langenberg.

27. The Skeletal Dysplasias: Clinical-Molecular Correlations:David L. Rimoin, Daniel Cohn, Deborah Krakow, William Wilcox, RalphS. Lachman, Yasemin Alanay.

28. Gene Therapy in Musculoskeletal Repair: Alan J. Nixon,Laurie R. Goodrich, Michael S. Scimeca, Tom H. Witte, Lauren V.Schnabel, Ashlee E. Watts, Paul D. Robbins.

29. Studies of Osteotropism on Both Sides of the BreastCancer-Bone Interaction: Jodie Moreau, Kristen M. Anderson , JoshuaR. Mauney, David Kaplan, and Michael Rosenblatt.

30. Effects of Adrenal Steroids on the Bone Metabolism ofChildren with Congenital Adrenal Hyperplasia: Karen Lin-Su andMaria I. New.

31. Quantitative Ultrasound Technology in Evaluating Bone Statusand Osteoporosis in Patients with Cushing's Syndrome: ValentinaCamozzi, Giovanni Luisetto, Monica Zangari, and Franco Lumachi.

32. Bone Mineral Density Improvement After SuccessfulParathyroidectomy in Pre- and Postmenopausal Women with PrimaryHyperparathyroidism. A Prospective Study: Franco Lumachi, ValentinaCamozzi,Mario Ermani, Frederica De Lotto, and GiovanniLuisetto.

33. Lumbar Spine Bone Mineral Density Changes in Patients withPrimary Hyperparathyroidism According to Age and Gender: FrancoLumachi, Valentina Camozzi, Mario Ermani, Alfredo Nardi, andGiovanni Luisetto.

34. Osteogenic Differentiation of Human Mesenchymal Bone MarrowCells in Silk Scaffolds is Regulated by Nitric Oxide: Petros D.Damoulis, Dimitrios E. Drakos, Eleni Gagari, David L. Kaplan.

35. IL-7 Modulats Osteoclastogenesis in Patients Affected bySolid Tumors: Ilaria Roato , Eva Gorassini, Giacomina Brunetti ,Maria Grano, Libero Ciuffreda , Antonio Mussa and RiccardoFerracini.

36. PTHrP and Tumorigenesis: Is There A Role in Prognosis?:Minoru Nishihara, Takashi Kanematsu, Mohammed S. Razzaque TakashiTaguchi