Natural Compounds and Their Role in Apoptotic Cell Signaling Pathways, Volume 1171ISBN: 978-1-57331-737-5
Paperback
400 pages
September 2009, Wiley-Blackwell
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Apoptosis is a highly regulated mechanism by which cells undergo
cell death in an active way. As one of the most challenging tasks
concerning cancer is to induce apoptosis in malignant cells,
researchers increasingly focus on natural products to modulate
apoptotic signaling pathways. This book reviews the main effects of
natural compounds on the different apoptotic signaling pathways,
including the intrinsic and extrinsic apoptosis pathways, the
NF-kB-mediated pathway, the PI3K/Akt signaling, and other main
pathways. Among the topic specially covered are:
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Effects of natural compounds on cancer cells
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Natural compounds as inducers of cell death
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Diet in health and disease
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Inflammation and cancer
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Natural compounds as kinase inhibitors
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Natural compounds in neurodegenerative diseases
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Natural compounds as inhibitors of ROS
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