Integrated Molecular Medicine for Neuronal and Neoplastic Disorders, Volume 1086

Preface: Integrated Molecular Medicine for Neuronal and Neoplastic Disorders.

Part I: Motor Neuron Diseases:.

1. Gene Expression Profiling Toward Understanding of ALS Pathogenesis: Fumiaki Tanaka, Jun-ichi Niwa, Shinsuke Ishigaki, Masahiko Yamamoto, Masahisa Katsuno, Manabu Doyu and Gen Sobue.

2. Untitled: Mimoun Azzouz.

3. Role of Polyunsaturated Fatty Acids for Misfolding Protein Aggregations; Implication for Neurodegenerative Diseases: Yeon-Jeong Kim and Ryosuke Takahashi.

4. Alleviating Neurodegeneration by an Anti-Cancer Agent – an Hsp90 Inhibitor (17-AAG): Masahiro Waza, Hiroaki Adachi, Masahisa Katsuno, Makoto Minamiyama,.

Fumiaki Tanaka, and Gen Sobue.

Part II: Alzheimer's Disease and Related Neurodegenerative Disorders:.

5. LRP in Amyloid-b Production and Metabolism: Guojun Bu, Judy Cam, and Celina Zerbinatti.

6. Neuronal Differentiation is Accompanied by Increased Levels of SNAP-25 Protein in Fetal Rat Primary Cortical Neurons- Implications in Neuronal Plasticity and Alzheimer's Disease: Jason A Bailey and Debomoy K. Lahiri.

7. Myosin Va Mutation in Rats is an Animal Model for the Human Hereditary Neurological Disease, Griscelli Syndrome Type 1: Yoshiko Takagishi and Yoshiharu Murata.

Part III: Neuroprotective Strategy for Neurodegenerative Diseases:.

8. Brain Keratan Sulfate and Glial Scar Formation: Haoqian Zhang, Kenji Uchimura and Kenji Kadomatsu.

9. The Direct and Indirect Effects of Serofendic Acid on Neuroprotection: Yukiko Doi, Jianfeng Liang, Reiko Kuno, Guiqin Zang, Jun Kawanokuchi, Izumi Yawata, Hideyuki Takeuchi, Tetsuya Mizuno, and Akio Suzumura.

10. Cytoplasmic Lipid Droplets: Re-discovery of an Old Structure as a Unique Platform: Toyoshi Fujimoto and Yuki Ohsaki.

Part IV: Neuronal Polarity and Psychiatric Disorders:.

11. Molecular mechanisms of Axon Specification and Neuronal Disorders: Takeshi Yoshimura, Nariko Arimura, and Kozo Kaibuchi.

12. Untitled: Naoya Sawamura, Akira Sawa et al.

13. Psychological, Neuroimaging and Biochemical Studies on Functional Association between Impulsive Behavior and the 5-HT2A Receptor Gene Polymorphism in Humans: Michio Nomura and Yasuyuki Nomura.

14. Investigating Gene-to-Behavior Pathways in Psychiatric Disorders: The Use of a Comprehensive Behavioral Test Battery on Genetically Engineered Mice: Keizo Takao and Tsuyoshi Miyakawa.

15. Animal Model of Schizophrenia: Dysfunction of NMDA Receptor-Signaling in Mice following Withdrawal from Repeated Administration of Phencyclidine: Toshitaka Nabeshima, Akihiro Mouri, Rina Murai, Yukihiro Noda.

Part V: Novel Targets for Cancer Therapy:.

16. Girdin, a Novel Actin-Binding Protein, and its Family of Proteins Possess Versatile functions in the AKT and WNT Signaling Pathways: Atsushi Enomoto, Jiang Ping, and Masahide Takahashi.

17. Biosignals Modulated by Tumor-associated Carbohydrate Antigens: Novel Targets for Cancer Therapy: Koichi Furukawa, Kazunori Hamamura, Aixinjueluo Wei, Keiko Furukawa.

18: Untitled: Naing Naing Mon, Michinari Hamaguchi et al.

19. SFK-STAT Pathway: An Alternative and Important Way to Malignancies: Fumihiko Hayakawa and Tomoki Naoe.

20. Pharmacogenetic Approach for Cancer Treatment-Tailored Medicine in Practice: Yoshinori Hasegawa, Yuichi Ando, Maki Ando, Naozumi Hashimoto, Kazuyoshi Imaizumi, and Kaoru Shimokata.

21. Involvement of DPPIV/CD26 in Epithelial Morphology and Suppressed Invasive Ability in Ovarian Carcinoma Cells: Hiroaki Kajiyama, Kiyosumi Shibata, Mikio Terauchi, Kazuhiko Ino, Akihiro Nawa, and Fumitaka Kikkawa