Sodium-Calcium Exchange and the Plasma Membrane Ca2+-ATPase in Cell Function: Fifth International Conference, Volume 1099ISBN: 978-1-57331-649-1
Paperback
400 pages
April 2007, Wiley-Blackwell
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Several important themes are addressed: (1) structure-function
relationships of the exchanger; (2) regulation of the exchanger;
(3) Na/Ca exchanger gene regulation; (4) cellular location and
targeting of the exchanger; (5) NC(K)X and PMCA KO mice; (6) Na/Ca
exchanger interactions with other proteins; (7) Na/Ca exchange in
cardiac function; (8) Na/Ca exchange in neuronal function; (9)
Ca2+-extruding mechanisms and apoptosis; (10) Na/Ca exchange in
smooth muscle, kidney, and endocrine function; (11) Na/Ca exchange
inhibitors: therapeutic opportunities. Experts in the field of the
plasma membrane Ca2+-ATPase (PMCA) have also contributed.
The rate of progress in this field has been rapidly increasing,
and new concepts have emerged regarding the relation between
molecular structure and physiological function. New ideas on
physiological modes of regulation have been increasingly testable
through the use of transgenic animal models.
This volume and the conference that preceded it continue the tradition of sharing information to fuel new advances in this exciting and important area of research.
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