Cell Injury: Mechanisms, Responses, and Therapeutics, Volume 1066ISBN: 978-1-57331-617-0
Paperback
340 pages
March 2006, Wiley-Blackwell
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Introduction: Raphael C. Lee, Florin Despa, and Kimm J. Hamann.
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Part I: Cell Structure and Integrity:.
1. Biological Water: Its Vital Role in Macromolecular Structure and Function: Florin Despa.
2. Thermal Stability of Proteins: John C. Bischof and Xiaoming He.
3. The Physics of the Interactions Governing Folding and Association of Proteins: Weihua Guo, Joan-Emma Shea, and R Stephen Berry.
4. Molecular Crowding Effects on Protein Stability: Florin Despa, Dennis P. Orgill, and Raphael C. Lee.
Part II: Modes of Cell Injury:.
5. Mechanical Cell Injury: Kenneth A. Barbee.
6. Cell Injury by Electric Forces: Raphael C. Lee.
7. Electroconformational Denaturation of Membrane Proteins: Wei Chen.
8. Heat Injury to Cells in Perfused Systems: Dennis P. Orgill, Stacy A. Porter, and Helena O. Taylor.
9. Cryo-Injury and Biopreservation: Alex Fowler and Mehmet Toner.
10. Oxidative Reactive Species in Cell Injury: Mechanisms in Diabetes Mellitus and Therapeutic Approaches: Leonid E. Fridlyand and Louis H. Philipson.
Part III: Cellular Responses to Injury:.
11. The Mechanisms of Cell Membrane Repair: A Tutorial Guide to Key Experiments: Richard A. Steinhardt.
12. The Role of Ca2+ in Muscle Cell Damage: Hanne Gissel.
13. Protein Denaturation and Aggregation: Cellular Responses to Denatured and Aggregated Proteins: Stephen C. Meredith.
14. Thermally Induced Injury and Heat-Shock Protein Expression in Cells and Tissues: Marissa Nichole Rylander, Yusheng Feng, Jon Bass, and Kenneth R. Diller.
15. Cellular Response to DNA Damage: Johnny Kao, Barry S. Rosenstein, Sheila Peters, Michael T. Milano, and Stephen J. Kron.
16. Autophagy: Ameeta Kelekar.
17. Magnetic Resonance Imaging of Changes in Muscle Tissues after Membrane Trauma: Hanne Gissel, Florin Despa, John Collins, Devkumar Mustafi, Katherine Rojahn, Greg Karczmar, and Raphael Lee.
Part IV: Therapeutics for Cell Injury:.
18. Na+-K+ Pump Stimulation Improves Contractility in Damaged Muscle Fibers: Torben Clausen.
19. Multimodal Strategies for Resuscitating Injured Cells: Jayant Agarwal, Alexandra Walsh, and Raphael C. Lee.
20. Membrane Sealing by Polymers: Stacey A. Maskarinec, Guohui Wu, and Ka Yee C. Lee.
21. A Surfactant Copolymer Facilitates Functional Recovery of Heat-Denatured Lysozyme: Alexandra M. Walsh, Devkumar Mustafi, Marvin W. Makinen, and Raphael C. Lee.
Index of Contributors