Therapeutic Oligonucleotides: Transcriptional and Translational Strategies for Silencing Gene Expression, Volume 1058

Yoon S. Cho-Chung (Editor), Alan M. Gewirtz (Editor), Cy A. Stein (Editor)

ISBN: 978-1-57331-609-5

Paperback

284 pages

December 2005, Wiley-Blackwell

List Price:	US $171.50
Government Price:	US $109.76
Enter Quantity: Buy

Therapeutic Oligonucleotides: Transcriptional and Translational Strategies for Silencing Gene Expression, Volume 1058 (1573316091) cover image

This is a Print-on-Demand title. It will be printed specifically to fill your order. Please allow an additional 10-15 days delivery time. The book is not returnable.

< >

The potential for the development of therapeutic oligonucleotides into clinical medicines and their use as basic research tools are explored in this volume, which is the proceedings of the 7th NIH Symposium on Therapeutic Oligonucleotides. The focus is on antisense, RNAi, triple-helix, gene repair, DNA chips, and CpG immune modulatory oligonucleotides.

Specific chapters address designing better siRNAs, splice switching oligonucleotides, selective delivery of oligonucleotides, and medicinal drugs by receptor-mediated endocytosis, development of a function overriding siRNA silencing in mammalian cells, transcription factor decoys, and modified oligonucleotide hybridization and genetic insertion.

NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.

ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.