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Pheochromocytoma: First International Symposium, Volume 1073

Karel Pacak (Editor), Graeme Eisenhofer (Editor)
ISBN: 978-1-57331-597-5
Paperback
328 pages
August 2006, Wiley-Blackwell
List Price: US $183.00
Government Price: US $117.12
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Pheochromocytoma: First International Symposium, Volume 1073 (1573315974) cover image

Pheochromocytoma is a rare neuroendocrine tumor with a highly variable presentation. There is lack of agreement about the most efficient and cost-effective methods for diagnosis and localization of the tumor, which can be lethal if not identified and treated promptly.Autopsy studies indicate that up to 50% of all cases remain undiagnosed until death.

Between 30 and 35% of the tumors have a hereditary basis. Development of malignancy is highly variable -- from less than 5% to more than 50% depending on the mutation; there is currently no effective cure.

This volume encompasses a number of themes in several sections: genetics and clinical decision-making; genetics, molecular pathways of tumorigenesis, and divergent phenotypes; kaleidoscopic presentations and a minefield for differential diagnosis of pheochromocytoma; biochemical diagnosis: can we reach consensus?; tumor localization and the evolving importance of functional imaging; and new molecular markers and targets for diagnosis and treatment of malignant pheochromcytoma.

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