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Catalysis in Asymmetric Synthesis, 2nd Edition

ISBN: 978-1-4051-9091-6
Hardcover
408 pages
March 2009, Wiley-Blackwell
List Price: US $194.95
Government Price: US $114.52
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Other Available Formats: Paperback

Asymmetric synthesis has become a major aspect of modern organic chemistry. The stereochemical properties of an organic compound are often essential to its bioactivity, and the need for stereochemically pure pharmaceutical products is a key example of the importance of stereochemical control in organic synthesis. However, achieving high levels of stereoselectivity in the synthesis of complex natural products represents a considerable intellectual and practical challenge for chemists.

Written from a synthetic organic chemistry perspective, this text provides a practical overview of the field, illustrating a wide range of transformations that can be achieved. The book captures the latest advances in asymmetric catalysis with emphasis placed on non-enzymatic methods.

Topics covered include:

  • Reduction of alkenes, ketones and imines
  • Nucleophilic addition to carbonyl compounds
  • Catalytic carbon-carbon bond forming reactions
  • Catalytic reactions involving metal carbenoids
  • Conjugate addition reactions

Catalysis in Asymmetric Synthesis bridges the gap between undergraduate and advanced level textbooks and provides a convenient point of entry to the primary literature for the experienced synthetic organic chemist.

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