ABC of Sepsis

Contributors vii

Preface ix

1 Introduction 1
Mitchell M. Levy

2 Defining the Spectrum of Disease 5
Ron Daniels

3 Identifying the Patient with Sepsis 10
Ron Daniels

4 Serious Complications of Sepsis 15
Hentie Cilliers Tony Whitehouse and Bill Tunnicliffe

5 The Pathophysiology of Sepsis 20
Edwin Mitchell and Tony Whitehouse

6 Initial Resuscitation 25
Tim Nutbeam

7 Microbiology and Antibiotic Therapy 29
Partha De and Ron Daniels

8 Infection Prevention and Control 36
Fiona Lawrence Georgina McNamara and Clare Galvin

9 The Role of Imaging in Sepsis 42
Morgan Cleasby

10 Presentations in Medical Patients 48
Nandan Gautam

11 Presentations in Surgical Patients 57
Jonathan Stewart and Sian Abbott

12 Special Cases: The Immunocompromised Patient 62
Manos Nikolousis

13 The Role of Critical Care 68
Julian Hull

14 Monitoring the Septic Patient 73
David Stanley

15 Novel Therapies in Sepsis 78
Gavin D. Perkins and David R. Thickett

16 Approaches to Achieve Change 83
Julian F. Bion and Gordon D. Rubenfield

Index 87