Metal Complex - DNA InteractionsISBN: 978-1-4051-7629-3
Hardcover
544 pages
May 2009, Wiley-Blackwell
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1. Sequence-Selective Binding of Transition Metal Complexes to DNA
2. Thermodynamic Models of Metal Ion -DNA.Interactions
3. Metal Ion Coordination in G-quadruplexes
4. Supramolecular Chemistry of Metal-Nucleobase Complexes
B Medical Applications
5. Platinum Drugs, Nucleotides, and DNA: the Role of Interligand Interactions,
nucleotides and DNA
6. Role of DNA Repair in Antitumor Effects of Platinum Drugs
7. Telomeres and Telomerase: Potential Targets for Platinum Complexes
8. Toward Photodynamic Therapy of Cancer with Platinum Group Metal Polyazine Complexes
9. Platinated Oligonucleotides: Synthesis and Applications for the Control of Gene
Expression
10. New Titanium and Ruthenium Anticancer Drugs and their Interaction with DNA
C DNA-Recognition - Nucleases and Sensors
11. Groove-Binding Ruthenium(II) Complexes as Probes of DNA Recognition
12. DNA Recognition and Binding by Peptide-Metal Complex conjugate
13. Artificial Restriction Agents - Hydrolytic Agents for DNA Cleavage
14. New Metallo-DNAzymes: Fundamental Studies of Metal-DNA Interactions and
Metal Sensing Applications
15. Two-metal Ion Dependent Catalysis in Nucleic Acid Enzymes
D Toxicological aspects
16. Mercury- DNA Interactions. Structural Studies on MercuryII -Mediated T-T Base-Pair with NMR Spectroscopy
17. Chromium-Induced DNA Damage and Repair
18. Arsenic and nickel: Mechanisms Affecting DNA Integrity