The Fetal and Neonatal Pulmonary Circulation

(E.K. Weir, S.L. Archer, J.T. Reeves).

Section I. Lung Growth and Development.

1. The Development of Concepts of the Ontogeny of the Pulmonary Circulation.

(A.M. Rudolph).

2. The de Novo Formation of Blood Vessels in the Early Embryo and in the Developing Lung. (C.J. Drake, C.D. Little).

3. Early Development of the Vascular System of the Mouse Lung: Ontogeny of Endothelial Cell Heterogeneity. (R. Auerbach, O. Mierzoeva, K.C. Meyer).

4. Structural Elements of Human Fetal and Neonatal Lung Vascular Development. (D.E. deMello).

Section II. Vascular Cell Growth and Differentiation.

5. Contribution of the Adventitial Fibroblast to Pulmonary Vascular Disease.

(K.R. Stenmark, M. Das, D. Bouchey, E.C. Dempsey).

6. The Role of Thrombospondins 1 and 2 in Vascular Development.

(L.C. Armstrong, T.R. Kyriakides, P. Bornstein).

7. Elastic Fiber Proteins in Pulmonary Vascular Development.

(J.M.W. Hausladen, R.P. Mecham).

8. Proteolytic Modulation of the Extracellular Matrix. (M. Rabinovitch).

9. Signal Transduction Kinases in the Regulation of Matrix Metalloproteinase-9 Expression in Vascular Smooth Muscle Cells. (A. Cho, M.A. Reidy).

10. Transcription Factors Controlling Cellular Proliferation During Vascular Repair. (R.C. Smith, T. Mano, K. Walsh).

11. Perlecan Heparan Sulfates in the Control of Vascular Smooth Muscle Cell Proliferation. (M.C.M. Weiser-Evans, K.R. Stenmark).

12. B-Myb Represses Collagen Gene Expression in Bovine Vascular Smooth Muscle Cells. (K.E. Kypreos, D.J. Marhamati, M.A. Nugent, G.E. Sonenshein).

13. Mechanical Forces in Vascular Growth and Development. (B.L. Langille).

Section III. Mechanisms of Hemodynamic Control in the Neonate.

14. Lung Arteriolar Endothelial Cell Proliferation at Birth: Possible Roles of Stretch and Hypoxia. (J.T. Reeves).

15. Physiologic Roles of Nitric Oxide in the Perinatal Pulmonary Circulation.

(S.H. Abman, J.P. Kinsella, T.A. Parker, L. Storme, T.D. Le Cras).

16. Regulation of Endothelial Nitric Oxide Synthase Expression in the Developing Lung. (P.W. Shaul).

17. The Role of Endothelin in Perinatal Pulmonary Vasoregulation.

(D.D. Ivy, S.H. Abman).

18. O2-Sensitive K+ Channel Activity in the Ovine Pulmonary Circulation Shifts with Maturation. (D.N. Cornfield, H.L. Reeve, E.K. Weir).

19. Regulation of Ion Channels in the Ductus Arteriosus. (H.L. Reeve, E.K. Weir).

20. Cytochrome P450 in the Contractile Tone of the Ductus Arteriosus: Regulatory and Effector Mechanisms. (F. Coceani).

21. Maturational Changes in the Human Pulmonary Vascular Resistance.

(J.C. Huhta, J. Rasanen).

22. The Pulmonary Vasculature in Congenital Diaphragmatic Hernia.

(R. Tibboel, S.M.K. Shehata, A.H. Guldemeester).

Index.