Chromatin and Gene Regulation: Molecular Mechanisms in Epigenetics

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1. Controlling transcription: shared aims and common mechanisms.

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2. Transcription in eukaryotes: the problems of complexity.

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3. The nucleosome: chromatin's structural unit.

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4. Histone tails: modifications and epigenetic information.

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5. Higher-order chromatin structures and nuclear organisation.

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6. Transcription in a chromatin environment.

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7. How the transcription machinery deals with chromatin.

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8. Chromatin remodelling machines.

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9. Heterochromatin.

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10. Long-term silencing of gene expression.

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11. Cellular memory and imprinting.

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12. Mechanisms of dosage compensation