Ashgate Handbook of Autonomic Nervous System AgentsISBN: 978-0-566-08384-6
Hardcover
498 pages
January 2001
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The Autonomic Nervous System (ANS) supplies all innervated
structures of the body other than skeletal muscle, and its effects
are therefore pervasive. The range of available ANS-active
compounds can effectively modulate any or all body systems. The
ANS-active agents include drugs used to treat a wide spectrum of
conditions including hypertension, myocardial insufficiency,
migraine, nasal congestion, obesity, Parkinson's disease, and
glaucoma. Drugs from an array of therapeutic categories, including
vasodilators, muscle relaxants, gastroprokinetics, and
bronchodilators, can be classified as ANS agents.
This Handbook contains records for all the major drugs that mimic or block the actions of ANS neurotransmitters or whose activities involve a direct effect on ANS neurotransmitter production, destruction or reuptake, or on junctional transmission. Monographs are provided for 1,996 ANS agents. For each main entry, the following information is provided: the chemical name and a list of proprietary names and synonyms; the Chemical Abstracts Service (CAS) Registry Number; the European Inventory of Existing Commercial Chemical Substances (EINECS) number, and the Merck Index (12th edition) number. The physical properties of each compound are described and the known biological activity and indicated applications are presented. The structure of each compound is provided, together with a summary of the acute toxicity data associated with it, and the manufacturers and suppliers of the drug are also given. Indexes, including a master index of names and synonyms, are appended.
This Handbook contains records for all the major drugs that mimic or block the actions of ANS neurotransmitters or whose activities involve a direct effect on ANS neurotransmitter production, destruction or reuptake, or on junctional transmission. Monographs are provided for 1,996 ANS agents. For each main entry, the following information is provided: the chemical name and a list of proprietary names and synonyms; the Chemical Abstracts Service (CAS) Registry Number; the European Inventory of Existing Commercial Chemical Substances (EINECS) number, and the Merck Index (12th edition) number. The physical properties of each compound are described and the known biological activity and indicated applications are presented. The structure of each compound is provided, together with a summary of the acute toxicity data associated with it, and the manufacturers and suppliers of the drug are also given. Indexes, including a master index of names and synonyms, are appended.