Gene Therapy Technologies, Applications and Regulations: From Laboratory to Clinic

Cationic Liposomes for Gene Therapy Applications (J. Clancy & E. Sorscher).

DNA Condensation and Receptor-mediated Gene Transfer (A. Ziady & T. Ferkol).

Retroviral Vectors (W. Günzburg & B. Salmons).

Lentiviral Vectors (A. Lever).

Adenoviral Vectors (S. Connelly).

Adeno-associated Viral Vectors (T. Flotte & B. Carter).

Advances in Engineering HSV Vectors for Gene Transfer to the Nervous System (M. Soares, et al.).

Mammalian Artificial Chromosomes: Prospects for Gene Therapy (T. Ebersole & C. Farr).

Gene Therapy for Severe Combined Immunodeficiency (A. Thrasher, et al.).

Gene Therapy for Haemophilia (R. Hoeben, et al.).

Cystic Fibrosis: Gene Therapy Approaches (N. Caplen).

Therapeutic Approaches to Haemoglobinopathies (Y. Beuzard).

Gene Therapy Approaches to Duchenne Muscular Dystrophy (S. Murphy & G. Dickson).

Lysosomal Storage Diseases (L. Lashford, et al.).

Prospects for Gene Therapy of HIV Infections and AIDS (C. Lee, et al.).

The Developemnt of the Regulatory Process in Europe for Biological Medicines: How it Affects Gene Therapy Products (A. Meager, et al.).

Developement and Regulation of Gene Therapy Drugs in Germany (K. Cichutek).

The Transfer of Technology from the Laboratory to the Clinic: In Process Controls and Final Product Testing (F. Borellini & J. Ostrove).

Good Laboratory Practice in the Research and Development Laboratory (A. Shepherd).

Facilities for Large-scale Production of Vectors Under GMP Conditions (J. Boyd).

Addendum.

Index.