Pharmacodynamics and Drug Development: Perspectives in Clinical Pharmacology

Neal R. Cutler (Editor), John J. Sramek (Editor), Prem K. Narang (Editor)

ISBN: 978-0-471-95052-3

Hardcover

512 pages

September 1994

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Description
Table of Contents
Author Information

Partial table of contents:

OVERVIEW OF PHARMACODYNAMICS.

Basic Pharmacodynamic Concepts and Models (R. Wills).

Factors Influencing Variability in Kinetics and Dynamics (P. Narang& R. Li).

General Perspectives on the Role of Metabolite in Pharmacokineticsand Pharmacodynamics (R. Seifert).

Regulatory Perspective: The Role of Pharmacokinetics andPharmacodynamics (L. Lesko & R. Williams).

APPLICATION OF PHARMACODYNAMICS IN SELECTED THERAPEUTICDOMAINS.

Theoretical Models for Developing Anxiolytics (P. Nickell & T.Uhde).

Pharmacodynamics of Antipsychotic Drugs in Schizophrenia (J. Sramek& G. Simpson).

Antihypertensive Drugs (L. Prisant & A. Carr).

Pharmacodynamics of Antineoplastic Agents (G. Rosner & M.Ratain).

Virology and Antiviral Drug Development (M. Amantea, et al.).

FRONTIERS IN PHARMACODYNAMICS: INSIGHT FROM MOLECULARAPPROACHES.

Muscarinic Receptors: Pharmacological Subtypes, Structure, Functionand Regulation (L. Mei, et al.).

Serotonin Receptor Subtypes (D. Pritchett).

Index.