From Genome to Therapy: Integrating New Technologies with Drug DevelopmentISBN: 978-0-471-62744-9
Hardcover
174 pages
November 2000
This is a Print-on-Demand title. It will be printed specifically to fill your order. Please allow an additional 10-15 days delivery time. The book is not returnable.
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Introduction (J. Venter).
Electrophoresis-Based Fluorescent Dideoxy-Terminator Sequencing (J. Efcavitch).
Genomic Impact on Pharmaceutical Development (J. Venter).
From Transcription Regulation to Cell Cycle Checkpoint (R. Cai, et al.).
Mass Spectrometry Resurrects Protein-Approaches in Functional Genomics (M. Mann).
A Clinical Molecular Scanner to Study Human Proteome Complexity (D. Hochstrasser, et al.).
From Proteomics to Functional Analysis (J. van Oostrum, et al.).
Microbial Genome Sequencing: New Insights into Physiology and Evolution (C. Fraser).
Pharmacogenetics and Pharmacogenomics in the Discovery and Development of Medicines (A. Roses).
Mutagenesis and Genomics in the Mouse: Towards Systematic Studies of Mammalian Gene Function (S. Brown).
Biological Annotation of the Drosophila Genome Sequence (G. Rubin).
Applications of High-Density Oligonucleotide Arrays (R. Lipshutz).
Plasmodium Falciparum: From Genomic Sequence to Vaccines and Drugs (S. Hoffman & D. Carucci).
Functional Analysis of the Yeast Genome by Precise Deletion and Parallel Phenotypic Characterization (E. Winzeler, et al.).
Patenting Genes and Gene Therapy: Legal and Ethical Aspects (J. Straus).
Ethical Issues: From Genome to Therapy (D. Magnus).
The Impact of Genomics on Drug Discovery (P. Goodfellow).
From Genome to Therapy: Industry Perspective (P. Herrling).
Final General Discussion.
Indexes.
Electrophoresis-Based Fluorescent Dideoxy-Terminator Sequencing (J. Efcavitch).
Genomic Impact on Pharmaceutical Development (J. Venter).
From Transcription Regulation to Cell Cycle Checkpoint (R. Cai, et al.).
Mass Spectrometry Resurrects Protein-Approaches in Functional Genomics (M. Mann).
A Clinical Molecular Scanner to Study Human Proteome Complexity (D. Hochstrasser, et al.).
From Proteomics to Functional Analysis (J. van Oostrum, et al.).
Microbial Genome Sequencing: New Insights into Physiology and Evolution (C. Fraser).
Pharmacogenetics and Pharmacogenomics in the Discovery and Development of Medicines (A. Roses).
Mutagenesis and Genomics in the Mouse: Towards Systematic Studies of Mammalian Gene Function (S. Brown).
Biological Annotation of the Drosophila Genome Sequence (G. Rubin).
Applications of High-Density Oligonucleotide Arrays (R. Lipshutz).
Plasmodium Falciparum: From Genomic Sequence to Vaccines and Drugs (S. Hoffman & D. Carucci).
Functional Analysis of the Yeast Genome by Precise Deletion and Parallel Phenotypic Characterization (E. Winzeler, et al.).
Patenting Genes and Gene Therapy: Legal and Ethical Aspects (J. Straus).
Ethical Issues: From Genome to Therapy (D. Magnus).
The Impact of Genomics on Drug Discovery (P. Goodfellow).
From Genome to Therapy: Industry Perspective (P. Herrling).
Final General Discussion.
Indexes.