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From Genome to Therapy: Integrating New Technologies with Drug Development

Gregory R. Bock (Editor), Dalia Cohen (Editor), Jamie A. Goode (Editor)
ISBN: 978-0-471-62744-9
Hardcover
174 pages
November 2000
List Price: US $235.00
Government Price: US $135.63
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Introduction (J. Venter).

Electrophoresis-Based Fluorescent Dideoxy-Terminator Sequencing (J. Efcavitch).

Genomic Impact on Pharmaceutical Development (J. Venter).

From Transcription Regulation to Cell Cycle Checkpoint (R. Cai, et al.).

Mass Spectrometry Resurrects Protein-Approaches in Functional Genomics (M. Mann).

A Clinical Molecular Scanner to Study Human Proteome Complexity (D. Hochstrasser, et al.).

From Proteomics to Functional Analysis (J. van Oostrum, et al.).

Microbial Genome Sequencing: New Insights into Physiology and Evolution (C. Fraser).

Pharmacogenetics and Pharmacogenomics in the Discovery and Development of Medicines (A. Roses).

Mutagenesis and Genomics in the Mouse: Towards Systematic Studies of Mammalian Gene Function (S. Brown).

Biological Annotation of the Drosophila Genome Sequence (G. Rubin).

Applications of High-Density Oligonucleotide Arrays (R. Lipshutz).

Plasmodium Falciparum: From Genomic Sequence to Vaccines and Drugs (S. Hoffman & D. Carucci).

Functional Analysis of the Yeast Genome by Precise Deletion and Parallel Phenotypic Characterization (E. Winzeler, et al.).

Patenting Genes and Gene Therapy: Legal and Ethical Aspects (J. Straus).

Ethical Issues: From Genome to Therapy (D. Magnus).

The Impact of Genomics on Drug Discovery (P. Goodfellow).

From Genome to Therapy: Industry Perspective (P. Herrling).

Final General Discussion.

Indexes.

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