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Genomics: The Science and Technology Behind the Human Genome Project

ISBN: 978-0-471-59908-1
Hardcover
632 pages
March 1999
List Price: US $243.25
Government Price: US $168.28
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DNA Chemistry and Biology.

A Genome Overview at the Level of Chromosomes.

Analysis of DNA Sequences by Hybridization.

Polymerase Chain Reaction and Other Methods for In Vitro DNA Amplification.

Principles of DNA Electrophoresis.

Genetic Analysis.

Cytogenetics and Pseudogenetics.

Physical Mapping.

Enhanced Methods for Physical Mapping.

DNA Sequencing: Current Tactics.

Strategies for Large-Scale DNA Sequencing.

Future DNA Sequencing Without Length Fractionation.

Finding Genes and Mutations.

Sequence-Specific Manipulation of DNA.

Results and Implications of Large-Scale DNA Sequencing.

Appendix.

Index.

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