The Tumour Microenvironment: Causes and Consequences of Hypoxia and AcidityISBN: 978-0-471-49959-6
Hardcover
312 pages
November 2001
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Introduction (Robert J Gillies).
Frontiers in the Measurement of Cell and Tissue pH (Robert J Gillies and Ronald M Lynch).
The Physiological Environment in Cancer Vascularization, Invasion and Metastasis (Zaver M Bhujwalla et al).
Why are Cancers Acidic? A Carrier-Mediated Diffusion Model for H+ Transport in the Interstitial Fluid (J R Griffiths et al).
pH and Therapy of Human Cancers (Jeffrey L Evelhoch).
Mathematical Models of Tumour Invasion Mediated by Transformation-Induced Alteration of Microenvironmental pH (Robert A Gatenby and Edward T Gawlinski).
pH Regulation of Renal Gene Expression (Norman P Curthoys et al)).
Genetic Determinants that influence Hypoxia-Induced Apoptosis (Rodolfo M Alarcon et al).
Genomic Instability in Cancer (Sara Rockwell et al).
pH, Hypoxia and Metastasis (R P Hill et al).
Modelling Tumour Acidity and Invasion (Steven D Webb et al).
pH, Aerobic Glycolysis and Vascular Endothelial Growth Factor in Tumour Growth (Jacques Pouyssé gur et al).
pH and Chemotherapy (Natarajan Raghunand).
The HIF Pathway: Implications for Patterns of Gene Expression in Cancer (Charles C Wykoff et al).
pH and Multidrug Resistance (Paul D Roepe).
'The Metabolism of Tumours' 70 Years Later (Gregg L Semenza et al).
The Multiple Mechanisms of Multidrug Resistance and Cellular pH (Sanford Simon).
Summing Up (Robert J Gillies).
Index of Contributors.
Subject Index.
Frontiers in the Measurement of Cell and Tissue pH (Robert J Gillies and Ronald M Lynch).
The Physiological Environment in Cancer Vascularization, Invasion and Metastasis (Zaver M Bhujwalla et al).
Why are Cancers Acidic? A Carrier-Mediated Diffusion Model for H+ Transport in the Interstitial Fluid (J R Griffiths et al).
pH and Therapy of Human Cancers (Jeffrey L Evelhoch).
Mathematical Models of Tumour Invasion Mediated by Transformation-Induced Alteration of Microenvironmental pH (Robert A Gatenby and Edward T Gawlinski).
pH Regulation of Renal Gene Expression (Norman P Curthoys et al)).
Genetic Determinants that influence Hypoxia-Induced Apoptosis (Rodolfo M Alarcon et al).
Genomic Instability in Cancer (Sara Rockwell et al).
pH, Hypoxia and Metastasis (R P Hill et al).
Modelling Tumour Acidity and Invasion (Steven D Webb et al).
pH, Aerobic Glycolysis and Vascular Endothelial Growth Factor in Tumour Growth (Jacques Pouyssé gur et al).
pH and Chemotherapy (Natarajan Raghunand).
The HIF Pathway: Implications for Patterns of Gene Expression in Cancer (Charles C Wykoff et al).
pH and Multidrug Resistance (Paul D Roepe).
'The Metabolism of Tumours' 70 Years Later (Gregg L Semenza et al).
The Multiple Mechanisms of Multidrug Resistance and Cellular pH (Sanford Simon).
Summing Up (Robert J Gillies).
Index of Contributors.
Subject Index.