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Understanding DNA and Gene Cloning: A Guide for the Curious, 4th Edition

ISBN: 978-0-471-43416-0
Paperback
369 pages
April 2003, ©2004
List Price: US $98.95
Government Price: US $73.56
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Chapter 1. Preview: Life as Interacting Molecules.

PART I. BASIC MOLECULAR GENETICS.

Chapter 2. Structure of DNA: Two Long, Interwound Chains.

Chapter 3. Reproducing DNA: Information Transfer from One Generation to the Next.

Chapter 4. Gene Expression: Cellular Use of Genetic Information.

PART II. MANIPULATION DNA.

Chapter 5. Microbial Growth: One-celled Organisms as Tools for Gene Cloning.

Chapter 6. Plasmids and Phages: Submicroscopic Parasites Used to Deliver Genes to Cells.

Chapter 7. Cutting and Joining DNA: Restriction Endonucleases and Ligases Used to Restructure DNA Molecules.

Chapter 8. Using Complementary Base Pairing: Hybridization, Probes, and Amplification using PCR.

Chapter 9. Cloning Genes: Isolation of a Hemoglobin Gene.

Chapter 10. Using Cloned Genes: Gene Structure, Expression Vectors, and Gene Function.

PART III. MODERN MOLECULAR GENETICS.

Chapter 11. Beyond the Central Dogma: A Sampling of Insights Derived from Gene Cloning.

Chapter 12. Retroviruses: AIDS and Gene Delivery.

Chapter 13. Cancer Genes: The Loss of Growth Control.

PART IV: HUMAN GENETICS.

Chapter 14. Heredity: Pattern of Inheritance and Genetic Instability.

Chapter 15. Application of Human Genetics: Genetic Testing, Gene Therapy, and DNA Fingerprinting.

PART V. WHOLE GENOMES.

Chapter 16. Genomics: Using Whole Genomes to Study Life.

Additional Reading.

Glossary.

Abbreviations.

Index.

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