The Amide Linkage: Structural Significance in Chemistry, Biochemistry, and Materials ScienceISBN: 978-0-471-35893-0
Hardcover
672 pages
January 2000
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The amide linkage is one of the most fundamental and widespread
chemical bonds in nature, underlying the properties of a vast array
of organic molecules, polymers, and materials, including peptides
and proteins. Arthur Greenberg, Curt Breneman, and Joel
Liebman’s peerless text provides comprehensive coverage of
the experimental, structural, and computational findings that shed
light on the chemical and physical properties of the amide linkage,
as well as its emerging applications in materials and
biotechnology.
Chapters in The Amide Linkage highlight how this chemical bond factors in the design of enzyme inhibitors, cyclic peptides, antibacterial agents, and emerging nanotechnology applications. This one-of-a-kind study also:
Chapters in The Amide Linkage highlight how this chemical bond factors in the design of enzyme inhibitors, cyclic peptides, antibacterial agents, and emerging nanotechnology applications. This one-of-a-kind study also:
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Discusses selected aspects of chemical reactions, structure, bonding, and energetics of the amide bond, including amide rotational barriers, stereochemistry, complexation, spectroscopy, and thermochemistry
- Presents specific applications to supramolecular and
stereospecific synthesis
- Discusses ke y aspects of peptide and protein
chemistry–such as molecular recognition, conformation, and
folding–in terms of the amide linkage
- Includes chapters contributed by numerous eminent chemists and biochemists
Organic, medicinal, polymer, and physical chemists, as well as biochemists and materials scientists, will find The Amide Linkage to be an invaluable addition to their professional libraries.