Epidemiologic Research: Principles and Quantitative Methods

Key Issues in Epidemiologic Research: An Overview.

OBJECTIVES AND METHODS OR EPIDEMIOLOGIC RESEARCH.

Fundamentals of Epidemiologic Research.

Types of Epidemiologic Research.

Design Options in Observational Studies.

Typology of Observational Study Designs.

Measures of Disease Frequency: Incidence.

Other Measures of Disease Frequency.

Measures of Association.

Measures of Potential Impact and Summary of the Measures.

VALIDITY OF EPIDEMIOLOGIC RESEARCH.

Validity: General Considerations.

Selection Bias.

Information Bias.

Confounding.

Confounding Involving Several Risk Factors.

PRINCIPLES AND PROCEDURES OF EPIDEMIOLOGIC ANALYSIS.

Statistical Inferences About Effect Measures: SimpleAnalysis.

Overview of Options for Control of Extraneous Factors.

Stratified Analysis.

Matching in Epidemiologic Studies.

Interaction, Effect Modification, and Synergism.

Modeling: Theoretical Considerations.

Modeling: Analysis Strategy.

Applications of Modeling with No Interaction.

Applications of Logistic Regression with Interaction, UsingUnconditional ML Estimation.

Applications of Modeling: Conditional Likelihood Estimation.

Appendices.

Index.