Cell Death

Gerry Melino (Editor), David Vaux (Editor)

ISBN: 978-0-470-71573-4

Hardcover

376 pages

March 2010

List Price:	US $183.00
Government Price:	US $105.56
Enter Quantity: Buy

This is a Print-on-Demand title. It will be printed specifically to fill your order. Please allow an additional 15-20 days delivery time. The book is not returnable.

< >

Contributors.

Preface.

The Siren’s Song: This Death That Makes Life Live (Gerry Melino, Richard A Knight and Jean-Claude Ameisen).

The Origin and Evolution of Programmed Cell Death (Jean Claude Ameisen).

Cell Death in C. elegans (Ataman Sendoel and Michael O Hengartner).

Caspases and Cell Death (Lorraine D Hernandez, Caroline Houde, Maarten Hoek, Brent Butts, Donald W Nicholson and Huseyin Mehmet).

The Apoptosome: The Executioner of Mitochondria-mediated Apoptosis (Elisabetta Ferraro and Francesco Cecconi).

Caspases, Substrates and Sequential Activation (John G Walsh and Seamus J Martin).

Dismantling the Apoptotic Cell (Paula Deming and Sally Kornbluth).

The BCL-2 Family Proteins – Key Regulators and Effectors of Apoptosis (David L Vaux).

BH3-only Proteins (Lina Happo, Andreas Strasser and Clare L Scott).

Mitochondrial Outer Membrane Permeabilization (Melissa J Parsons and Douglas R Green).

Mitochondria Fusion and Fission (Giovanni Benard, Guihong Peng and Mariusz Karbowski).

Death Receptors (Peter H Krammer and Inna N Lavrik).

Death Receptors at the Molecular Level: Therapeutic Implications (Marion MacFarlane).

Death Receptor-induced Necroptosis (Wim Declercq, Franky Van Herreweghe, Tom Vanden Berghe and Peter Vandenabeele).

Inhibitor of Apoptosis (IAP) and BIR-containing Proteins (David L Vaux).

Structures, Domains and Functions in Cell Death (DD, DED, CARD, PYD) (Hao Wu and Yu-Chih Lo).

Structure and Function of IAP and Bcl-2 Proteins (Mark G Hinds, Peter D Mace and Catherine L Day).

Engulfment of Apoptotic Cells and its Physiological Roles (Rikinari Hanayama, Masanori Miyanishi, Hiroshi Yamaguchi, Jun Suzuki and Shigekazu Nagata).

Autophagy (María Isabel Colombo and Hans-Uwe Simon).

Autophagy in Nonmammalian Systems (Jahda H Hill and Eric H Baehrecke).

Apoptosis: Regulatory Genes and Disease (James E Vince and John Silke).

Caspases in Inflammation and Immunity (Philippe M LeBlanc and Maya Saleh).

Immunity, Granzymes and Cell Killing (Nigel J Waterhouse, Olivia Susanto, Karin A Sedelies and Joseph A Trapani).

P53 and Cell Death (Kamil Wolyniec, Sue Haupt and Ygal Haupt).

Cornification of the Skin: A Non-apoptotic Cell Death Mechanism (E Candi, RA Knight and G Melino).

Apoptosis: Inherited Disorders (Helen C Su and Michael J Lenardo).

From Reactive Oxygen and Nitrogen Species to Therapy (Scott R McKercher, Tomohiro Nakamura and Stuart A Lipton).

Microbial Inhibitors of Apoptosis (Georg Häcker).

Drug Discovery in Apoptosis (Tom O’Brien and Vishva M Dixit).

Subject Index.