Functionalised N-Heterocyclic Carbene ComplexesISBN: 978-0-470-71215-3
Hardcover
364 pages
March 2010
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N-heterocyclic carbenes (NHCs) have found increasing use as
reagents for a range of organic transformations and in asymmetric
organocatalysis. The performance of these molecules can be improved
and tuned by functionalisation. Functionalised carbenes can anchor
free carbenes to the metal site, introduce hemilability, provide a
means to immobilise transition metal carbene catalysts, introduce
chirality, provide a chelate ligand or bridge two metal centres.
NHC can be attached to carbohydrates and campher, derived from
amino acids and purines, they can be used as organocatalysts
mimicking vitamin B1 or as weak “solvent” donors in
lanthanide chemistry.
Functionalised N-Heterocyclic Carbene Complexes describes major trends in functionalised NHC ligands, aiming to assist readers in their attempts to develop and apply their own functionalised carbenes. After an introduction to the chemistry and behaviour of NHC, the book gives a detailed description of functionalised carbenes and their complexes according to a range of functional groups, each with a discussion of the synthetic route, structure, stability and performance.
Functionalised N-Heterocyclic Carbene Complexes is an essential guide to fine-tuning this important class of compounds for practitioners, researchers and advanced students working in synthetic organometallic and organic chemistry and catalysis.