Aggregation of Therapeutic ProteinsISBN: 978-0-470-41196-4
Hardcover
484 pages
August 2010
This is a Print-on-Demand title. It will be printed specifically to fill your order. Please allow an additional 15-20 days delivery time. The book is not returnable.
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"Among their topics are fundamental structures and behaviors of
proteins; protein aggregation pathways, kinetics, and
thermodynamics; the identification and impact of aggregate-prone
regions in proteins and therapeutic monoclonal antibodies; external
factors affecting protein aggregation; experimental detection and
characterization of protein aggregates; approaches to controlling
it during bulk production; effects of formulation interfaces, and
drug product manufacturing operations on aggregation and particle
formation; approaches to managing it in product development;
aggregation and immunogenicity of therapeutic proteins; and a
regulatory perspective on aggregates as a product quality
attribute." (SciTech Book News, December 2010)