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Aggregation of Therapeutic Proteins

Wei Wang (Editor), Christopher J. Roberts (Editor)
ISBN: 978-0-470-41196-4
Hardcover
484 pages
August 2010
List Price: US $159.00
Government Price: US $110.04
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Aggregation of Therapeutic Proteins (0470411961) cover image
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"Among their topics are fundamental structures and behaviors of proteins; protein aggregation pathways, kinetics, and thermodynamics; the identification and impact of aggregate-prone regions in proteins and therapeutic monoclonal antibodies; external factors affecting protein aggregation; experimental detection and characterization of protein aggregates; approaches to controlling it during bulk production; effects of formulation interfaces, and drug product manufacturing operations on aggregation and particle formation; approaches to managing it in product development; aggregation and immunogenicity of therapeutic proteins; and a regulatory perspective on aggregates as a product quality attribute." (SciTech Book News, December 2010)

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