Chiral Separation Methods for Pharmaceutical and Biotechnological ProductsISBN: 978-0-470-40691-5
Hardcover
November 2010
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Preface.
1 Overview of Chiral Separations (Satinder Ahuja).
2 Regulatory & Development Considerations of Chiral Compounds (Robert L. Zeid).
3 Basic Considerations in Method Development for Chiral Compounds (Satinder Ahuja).
4 Separations of Chiral Compounds on Polysaccharide Columns (Clinton W. Amoss and Norbert M. Maier).
5 Chiral Separations by Various Techniques (Jian G. Ning).
6 Chiral Discrimination Study for Polysaccharide Based Chiral Stationary Phase (Yun K. Ye).
7 Comparison of Chiral Chromatographic Columns for Pharmaceuticals (Gregory K. Webster).
8 Chiral Separation Screens for Pharmaceutical Analysis and Purification in an Industrial Laboratory Environment (Robert DePianta, Kenneth Douville, Beverly Nickerson, and Ricardo E. Borjas).
9 The Separation of Enantiomers by Gas Chromatography on Chiral Stationary Phases (Volker Schurig).
10 Separations of Chiral Compounds by SFC (Ziqiang Wang).
11 Chiral Separations by Capillary Electrophoresis (Debby Mangelings and Yvan Vander Heyden).
12 High-Throughput Screening and Method-Development Strategies to Separate Chiral Drug Compounds in HPLC, SFC, and CE (Hasret Ates, Debby Mangelings and Yvan Vander Heyden).
13 Use of Enantioselective Synthesis and Preparative Chiral Chromatography to Access a Challenging Enantiopure Pharmaceutical Candidate from a Mixture of Four Stereoisomers (Christopher J. Welch, Derek H. Henderson, William R. Leonard, Mirlinda Biba, Mike Zacuto, Fred Fleitz, Amude Kassim, Cheng-yi Chen, and Peter Sajonz).
14 A Look into the Future: Chiral Analysis Using Chemical Sensor Technology (Gregory K. Webster and William J. Buttner).
15 Chirality of Biomolecules and Biotechnology Products (Satinder Ahuja).
Index.