Mass Spectrometry in Drug Metabolism and Disposition: Basic Principles and ApplicationsISBN: 978-0-470-40196-5
Hardcover
800 pages
May 2011
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MIKE S. LEE, PhD, is President of Milestone Development
Services. His recent work has involved the development of automated
orthogonal control systems for electrospray ionization. Formerly,
Dr. Lee was director of analytical research and development at
Bristol-Myers Squibb (BMS) Pharmaceutical Research Institute where
he led interdisciplinary teams that contributed to the Food and
Drug Administration's approval of Buspar® and Serzone®,
and the accelerated development and approval of Taxol®. In
addition, he has authored over forty scientific papers and issued
patents.
MINGSHE ZHU, PhD, is a drug metabolism researcher at Bristol-Myers Squibb, where he leads a team that investigates biotransformation in new drug discovery and preclinical drug metabolism and pharmacokinetics in development. His teams have provided key metabolism and disposition information for regulatory approval of Abilify® and NDA submission of Dapagliflozin. Dr. Zhu's research interests include LC/MS technology, optimization of ADME properties, metabolic activation, and regulatory drug metabolism. He has been frequently invited to speak and teach short courses at conferences/workshops and has coauthored over sixty research articles and one book.