Lead Generation Approaches in Drug Discovery

CONTRIBUTORS.

1 Lead Discovery: The Process (William F. Michne).

2 High Throughput Screening Approach to Lead Discovery (Zoran Rankovic, Craig Jamieson, and Richard Morphy).

3 In Silico Screening (Dagmar Stumpfe, Hanna Geppert, and Jürgen Bajorath).

4 Fragment-Based Lead Discovery (Jeffrey S. Albert).

5 Design of Multitarget Ligands (Richard Morphy and Zoran Rankovic).

6 De novo Drug Design (Gisbert Schneider, Markus Hartenfeller, and Ewgenij Proschak).

7 Role of Natural Products in Drug Discovery (Hugo Lachance, Stefan Wetzel, and Herbert Waldmann).

8 Early Screening for ADMET Properties (Dennis A. Smith).

9 Role of Chemistry in Lead Discovery (Roland E. Dolle and Karin Worm).

INDEX.