Colloidal Nanoparticles in Biotechnology

Preface ix

Contributors xi

1. Reactive Nanocolloids for Nanotechnologies and Microsystems 1
Christian Pichot

2. Nanoparticles Comprising pH/Temperature-Responsive Amphiphilic Block Copolymers and Their Applications in Biotechnology 31
Peihong Ni

3. Evolution in Malaria Disease Detection: From Parasite Visualization to Colloidal-Based Rapid Diagnostic 65
Duangporn Polpanich, Pramuan Tangboriboonrat, and Abdelhamid Elaissari

4. Antigen-Antibody Interactions Detected by Quasi-Elastic Light Scattering and Electrophoretic Mobility Measurements – A New Concept for Latex Immunodiagnostic Test 95
Teresa Basinska and Stanislaw Slomkowski

5. Biospecific Reactions by Affinity Latexes from Diagnostics to Multiplex Assay 117
Haruma Kawaguchi

6. Fluorescent Colloidal Particles as Detection Tools in Biotechnology Systems 133
Igor Nabiev, Alyona Sukhanova, Mikhail Artemyev, and Vladimir Oleinikov

7. Biofunctionalized Magnetic Micro/Nanoparticles for Biosensing Technologies 169
Nicole Jaffrezic-Renault, Claude Martelet, Yann Chevolot, and Jean-Pierre Cloarec

8. Colloids, Biotechnology, and Microfluidics 199
Cecile Cottin-Bizonne and Rosaria Ferrigno

9. Gas Sensors Based on Ultrathin Films of Conducting Polymers and Nanocomposites 223
Manoj K. Ram, Ozlem Yavuz, and Matt Aldissi

10. Force Measurements between Emulsion Droplets As a New Tool for Medical Diagnostics 247
Abdelhamid Elaissari, Celine Genty, and Olivier Mondain-Monval

11. Particles for Protein Analysis in Microfluidic Systems 275
Anne Le Nel, Myriam Taverna, and Jean-Louis Viovy

12. Semicarbazide/a-oxo Aldehyde Site-Specific Ligation Chemistry: From Peptide Microarrays to the Micropatterning of Polycarbonate or Titanium Oxide Using Silica Nanoparticles 299
Ouafaa El-Mahdi, Vianney Souplet, Olivier Carion, Clement Roux, Jean-Michel Garcia, Celine Maillet, Christophe Olivier, Oleg Melnyk and Jean-Olivier Durand

13. Electrical Detection of Antibodies from Human Serum Based on the Insertion of Gold-Labeled Secondary Antibodies into Microor Nanogaps 329
Lionel Marcon, Didier Stie´venard, and Oleg Melnyk

Index 353