Protein Targeting with Small Molecules: Chemical Biology Techniques and Applications

Preface.

Chapter 1: Chemical biology based on the small molecule-protein interaction (Hiroyuki Osada).

Chapter 2: Target Profiling of Small Molecules (Leonid L. Chepelev, and Michel Dumontier).

Chapter 3: Novel application of affinity beads (Yasuaki Kabe, Mamoru Hatakeyama, Satoshi Sakamoto, Kousuke Nishio, and Hiroshi Handa).

Chapter 4: Immolization of small molecules on solid phase (Naoki Kanoh, and Hiroyuki Osada).

Chapter 5: Application of phage display technique to identify the target protein (Yoon Sun Cho and Ho Jeong Kwon).

Chapter 6: Development of fluorescent probes for small molecules (Adrian P. Neal, and Carsten Schultz).

Chapter 7: Development of small molecule ligands and inhibitors (Leonid L. Chepelev, Nikolai L. Chepelev, Hooman Shadnia, William G. Willmore, James S. Wright, and Michel Dumontier).

Chapter 8: Interaction of biological response modifier with proteins (Yuichi Hashimoto).

Chapter 9: Chemical biology of cell motility inhibitors (Tatsuro Kawamura, Mitsuhiro Kitagawa, and Masaya Imoto).

Chapter 10: Chemical biology of cell surface oligosaccarides (Prabhani U. Atukorale, Sean S. Choi, Udayanath Aich, Christopher T. Campbell, M. Adam Meledeo, and Kevin J. Yarema).

Chapter 11: Chemical genomics based on yeast genetics (Shinichi Nishimura, and Yoko Yashiroda Minoru Yoshida).

Chapter 12: Data Fact of small molecules and their target proteins (Takeo Usui, Akiko Saito, and Hiroyuki Osada).

Index.