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Dopamine Transporters: Chemistry, Biology, and Pharmacology

Mark L. Trudell (Editor), Sari Izenwasser (Editor), Binghe Wang (Series Editor)
ISBN: 978-0-470-11790-3
Hardcover
472 pages
July 2008
List Price: US $161.25
Government Price: US $111.32
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Dopamine Transporters: Chemistry, Biology, and Pharmacology (0470117907) cover image

Contributors.

Preface.

Part I: Biochemistry and Molecular Biology.

Chapter 1: The Dopamine Transporter: An Anatomical Perspective (Hilary R. Smith, Thomas J. Beveridge, Colleen A. Hanlon, Linda J. Porrino).

Chapter 2: Dopamine Transporter, Disease States and Pathology (Deborah C. Mash).

Chapter 3: Cloning and Genetic Analysis of Dopamine Transporters (David J. Vandenbergh).

Chapter 4: Molecular Structure and Composition of Dopamine Transporters (M. Laura Parnas and Roxanne A. Vaughan).

Chapter 5: Electrochemical Characterization of Dopamine Transporters (Evgeny A. Budygin and Sara R. Jones).

Part II: Medicinal Chemistry.

Chapter 6: Tropane-Based Dopamine Transporter-uptake Inhibitors (Scott P. Runyon and F. Ivy Carroll).

Chapter 7: The Benztropines: Atypical Dopamine-Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter (Amy Hauck Newman and Jonathan L. Katz).

Chapter 8. Structure-Activity Relationship of GBR 12909 Ligands (Thomas E. Prisinzano and Kenner C. Rice).

Chapter 9: Structure-Activity Relationship Study of Piperidine Derivatives for Dopamine Transporters (Prashant S. Kharkar, Maarten E. A. Reith, and Aloke K. Dutta).

Chapter 10: Non-Nitrogen-Containing Dopamine Transporter-Uptake Inhibitors (Peter C. Meltzer).

Chapter 11: Dopamine-Releasing Agents (Bruce E. Blough).

Part III: Pharmacology.

Chapter 12: PET/SPECT Imaging Studies of the Plasma Membrane Dopamine Transporter. (Paul Cumming, Weiguo Ye, Dean F. Wong).

Chapter 13: In Vitro Studies of Dopamine Transporter Function and Regulation (Brian R. Hoover, Bruce H. Mandt and Nancy R. Zahniser).

Chapter 14: In Vivo Studies of Dopamine Transporter Function (Jane B. Acri).

Index.

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