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An Introduction to Statistics in Early Phase Trials

ISBN: 978-0-470-05985-2
Hardcover
272 pages
March 2010
List Price: US $133.00
Government Price: US $76.76
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An Introduction to Statistics in Early Phase Trials  (0470059850) cover image

Chapter 1 Early phase trials

Chapter 2 Introduction to pharmacokinetics

Chapter 3 Sample size calculations for clinical trials

Chapter 4 Crossover trial basics

Chapter 5 Multi-period crossover trials

Chapter 6 First time into man

Chapter 7 Bayesian and frequentist methods

Chapter 8 First-time-into-new-population studies

Chapter 9 Bioequivalence studies

Chapter 10 Other Phase I trials

Chapter 11 Phase II trials: general issues

Chapter 12 Dose–response studies

Chapter 13 Phase II trials with toxic therapies

Chapter 14 Interpreting and applying early phase trial results

Chapter 15 Go/No-Go criteria

Appendix

References

Index

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