Fatty Acid and Lipotoxicity in Obesity and Diabetes

Editors: Gregory Bock (Organizer) and Jamie Goode.

This symposium is based on a proposal made by Peng Li.

Bruce M. Spiegelman - Chair’s introduction.

Bruce M. Spiegelman - Transcriptional control of energy homeostasis through the PGC1 coactivators.
Discussion.

Stephen O’Rahilly -  Human obesity and insulin resistance: lessons from experiments of nature.
Discussion.

Deborah M. Muoio and Timothy R. Koves - Lipid-induced metabolic dysfunction in skeletal muscle.
Discussion.

Alan D. Attie, Matthew T. Flowers, Jessica B. Flowers, Albert K. Groen, Folkert Kuipers and James M. Ntambi - Stearoyl-CoA desaturase deficiency, hypercholesterolaemia, cholestasis and diabetes.
Discussion.

Karen Reue - The role of lipin 1 in adipogenesis and lipid metabolism. Discussion.

David Carling - The role of the AMP-activated protein kinase in the regulation of energy homeostasis.
Discussion.

Gökhan S. Hotamisligil - Endoplasmic reticulum stress and inflammation in obesity and type 2 diabetes.
Discussion.

Ira Tabas, Tracie Seimon, Jerry Arellano, Yankun Li, Fabien Forcheron, Dongying Cui, Seongah Han, Chien-Ping Liang, Alan Tall and Domenico Accili - The impact of insulin resistance on macrophage death pathways in advanced atherosclerosis.
Discussion.

Sandra Lobo and David A. Bernlohr - Fatty acid transport in adipocytes and the development of insulin resistance.
Discussion.

Paul N. Black and Concetta C. DiRusso - Vectorial acylation: linking fatty acid transport and activation to metabolic trafficking.
Discussion. 

Günther Daum, Andrea Wagner, Tibor Czabany, Karlheinz Grillitsch and Karin Athenstaedt - Lipid storage and mobilization pathways in yeast.
Discussion. 

John Zhong Li and Peng Li - Cide proteins and the development of obesity.  Discussion.

General discussion I.
Visualizing brown adipose tissue with FDG-PET.

Takashi Kadowaki, Toshimasa Yamauchi, Naoto Kubota, Kazuo Hara and Kohjiro Ueki - Adiponectin and adiponectin receptors in obesity-linked insulin resistance.
Discussion.

Gabriel Pascual, Amy L. Sullivan, Sumito Ogawa, Amir Gamliel, Valentina Perissi, Michael G. Rosenfeld and Christopher K. Glass -Anti-inflammatory and antidiabetic roles of PPARγ.
Discussion.

Final discussion.
Nutrition, ageing and lipotoxicity.

Index of contributors.

Subject index.