Clinical Diabetes Research: Methods and Techniques

2 Methods for the Assessment of b-Cell Function In Vivo.

3 Assessment of Insulin Sensitivity from Steady-State and Dynamic Tests. 

4 Glucose Clamp Techniques. 

5 Methods of Assessment of Counterregulation to Hypoglycaemia.

6 Glucose Kinetics: Measurement of Flux Rates.

7 Xenobiotics as Probes of Carbohydrate Metabolism.

8 Tracing Hepatic Glucose and Glycogen Fluxes with 2H2O. 

9 Lipid Kinetics.

10 Protein and Amino Acid Kinetics.

11 Assessment of Metabolic Fluxes by In Vivo MR Spectroscopy.

12 Positron Emission Tomography in Metabolic Research.

13 Assessment of Body Fat Content and Distribution.

14 Tissue Biopsies in Diabetes Research.

15 Assessment of Vascular Function.

16 Cardiovascular Autonomic Function Testing.

17 Nerve Function Testing. 

18 Kidney Function. 

19 Techniques for the Investigation of the Eye in Diabetes.

20 Basics of Molecular Genetics: Lessons from Type 2 Diabetes. 

21 Good Clinical Practice: Friend or Foe? 

22 Statistical Considerations in Diabetes Trials. 

Index.